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Integrated management of cardiac failure: the cardiac failure clinic

Daniel LOISANCE

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 20-25 doi: 10.1007/s11684-011-0106-1

Abstract:

The prevalence of the risk factors and the risk of cardiac failure are both increasing in China.The wide range of clinical presentations of cardiac failure (acute or chronic) and of therapeutic approachesintegration within the same structure of the various experts involved in the diagnosis and the treatment of cardiacIn these centers, collaboration should replace competition between the medical and the surgical cardiac

Keywords： cardiac failure     cardiac transplantation     mechanical circulatory support    

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Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in

Frontiers of Medicine   Pages 939-956 doi: 10.1007/s11684-023-0987-9

Abstract: To this end, 12 645 cardiac cells were generated from embryonic day 17.5 and postnatal days 2 and 8 miceThree cardiac developmental paths were identified: two switching to cardiomyocytes (CM) maturation withThese findings could improve the understanding of MNDCM heterogeneity and cardiac development, thus providingnew clues for approaches to effective cardiac regeneration.

Keywords： mononuclear diploid cardiomyocytes     cell–cell communication     cardiac fibroblast     single-cell RNA sequencing     cardiac regeneration    

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Association of cardiac disease with the risk of post-lung transplantation mortality in Chinese recipients

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 58-67 doi: 10.1007/s11684-022-0937-y

Abstract: Kaplan–Meier estimates showed that recipients with cardiac abnormalities had a significantly increasedAfter adjusting for potential confounders, cardiac abnormality was shown to be independently associated

Keywords： cardiac disease     mortality     aged population     lung transplantation    

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Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock

Muhammad Furqan,Yamei Chen,Akintunde Akinleye,Judy Sarungbam,Alan Gass,Karen Seiter,Delong Liu

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 254-258 doi: 10.1007/s11684-014-0319-1

Abstract: Here we report a case of cardiac involvement by mantle cell leukemia leading to cardiogenic shock which

Keywords： mantle cell lymphoma     bendamustine     cardiogenic shock    

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Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 19-24 doi: 10.1007/s11684-008-0005-2

Abstract: the effects of RNA interference (RNAi) targeting angiotensin 1a receptor (AT1a) on blood pressure and cardiactargeting AT1a receptor inhibits the development of renovascular hypertension and the accompanying cardiac

Keywords： therapy     Sprague     administration     cardiac hypertrophy     valsartan    

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Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis

Wei Gong,Mengwen Yan,Junxiong Chen,Sandip Chaugai,Chen Chen,Daowen Wang

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 445-455 doi: 10.1007/s11684-014-0378-3

Abstract: Whether and how it ameliorates cardiac fibrosis, a major cause of diastolic dysfunction and heart failureIn control mice, 4 weeks of TAC induced significant cardiac dysfunction, cardiac fibrosis, and cardiacSildenafil treatment markedly prevented TAC-induced cardiac dysfunction, cardiac fibrosis and cardiacIn isolated cardiac fibroblasts, sildenafil blocked TGF-β1-induced cardiac fibroblast transformationthrough CREB activation in cardiac fibroblasts.

Keywords： PDE5     cardiac fibrosis     TGF-β     CREB    

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Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling

Samuel Chege Gitau,Xuelian Li,Dandan Zhao,Zhenfeng Guo,Haihai Liang,Ming Qian,Lifang Lv,Tianshi Li,Bozhi Xu,Zhiguo Wang,Yong Zhang,Chaoqian Xu,Yanjie Lu,Zhiming Du,Hongli Shan,Baofeng Yang

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 444-456 doi: 10.1007/s11684-015-0421-z

Abstract: Changes in the cardiac structure and function were assessed through echocardiography and transmission

Keywords： aspirin     Akt     cardiac hypertrophy     GSK-3β     Wnt/β-catenin    

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PAK1 is a novel cardiac protective signaling molecule

Yunbo Ke,Xin Wang,Xu Yu Jin,R. John Solaro,Ming Lei

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 399-403 doi: 10.1007/s11684-014-0380-9

Abstract:

We review here the novel cardiac protective effects of the multifunctional enzyme, p21-activated kinasereview, we assemble an overview of the recent findings on PAK1 signaling in the heart, particularly its cardiacWe present a model for PAK1 signaling that provides a mechanism for specifically affecting cardiac cellularWe discuss the anti-adrenergic and antihypertrophic cardiac protective effects of PAK1, as well as its

Keywords： p21-activated kinase 1 (PAK1)     heart    

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Progressive failure analysis of notched composite plate by utilizing macro mechanics approach

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 3,   Pages 623-642 doi: 10.1007/s11709-021-0726-8

Abstract: In this study, gradual and sudden reduction methods were combined to simulate a progressive failure inUsing the presented method, a progressive failure is simulated based on a linear softening law priorto a catastrophic failure, and thereafter, sudden reduction methods are employed for modeling a progressivefailure.The proposed method is intended to predict the first ply failure (FPF), LPF, and dominant failure modes

Keywords： progressive failure     notched composite plate     Hashin failure criterion     macro mechanics approach     finite    

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Bending failure performance of a shield tunnel segment based on full-scale test and numerical analysis

Frontiers of Structural and Civil Engineering   Pages 1033-1046 doi: 10.1007/s11709-023-0973-y

Abstract: This study focuses on the bending failure performance of a shield tunnel segment.A full-scale test was conducted to investigate deformation and failure characteristics.During the loading, the bending failure process can be divided into four stages: the elastic stage, workingstage with cracks, failure stage, and ultimate stage.The characteristic loads between contiguous stages are the cracking, failure, and ultimate loads.

Keywords： shield tunnel     bearing capacity     failure mechanism     segment reinforcement    

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Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 1-17 doi: 10.1007/s11684-016-0439-x

Abstract:

Liver failure (LF) is defined as severe dysfunction in hepatic synthesis, detoxification, and metabolism

Keywords： liver failure     chronic liver failure     acute-on-chronic liver failure     diagnosis     prognosis     treatment    

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Surficial stability analysis of soil slope under seepage based on a novel failure mode

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 3,   Pages 712-726 doi: 10.1007/s11709-021-0729-5

Abstract: Therefore, a novel failure mode involving three sliding zones (upper tension zone, middle shear slidingSubsequently, the new failure mode was verified via a numerical finite element analysis based on theThe results obtained by the new failure mode agree well with those obtained by the numerical analysis

Keywords： soil slope     seepage     surficial failure mode     stress state     edge effects    

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LSSVM-based approach for refining soil failure criteria and calculating safety factor of slopes

Shiguo XIAO; Shaohong LI

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 7,   Pages 871-881 doi: 10.1007/s11709-022-0863-8

Abstract: The failure criteria of practical soil mass are very complex, and have significant influence on the safetyThe Coulomb strength criterion and the power-law failure criterion are classically simplified.machine (LSSVM), a machine learning model, is purposefully provided to establish a complex nonlinear failurepercentage error, and mean square error indicate that fitting precision of the machine learning-based failureBased on the proposed LSSVM approach to determine the failure criterion, the limit equilibrium method

Keywords： slope stability     safety factor     failure criterion     least square support vector machine    

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Study of high-strength CFRP bolted joints with failure- monitoring cone washers

Tsukasa KATSUMATA, Yoshihiro MIZUTANI, Akira TODOROKI, Ryosuke MATSUZAKI

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 3,   Pages 272-276 doi: 10.1007/s11465-011-0231-1

Abstract: The increase in failure load for the proposed joint was confirmed in finite-element method analyses and

Keywords： composite     bolted joint     failure monitoring     finite-element method    

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Analysis of stress and failure in rock specimens with closed and open flaws on the surface

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 5,   Pages 1222-1237 doi: 10.1007/s11709-021-0773-1

Abstract: The influence of closed and open surface flaws on the stress distribution and failure in rock specimensinvestigate the influences of the flaw inclination, friction coefficient and the confining stress on failureNumerical results show significant differences in the stress, displacement, and failure behavior of thesurface, an open flaw may play a destressing role in the rock and relocate the stress concentration and failureThe presented results in this article suggest that failure at the rock surface may be managed in a favorable

Keywords： surface flaw     heterogeneity     circular hole     numerical modeling     relative displacement    

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Title Author Date Type Operation

Integrated management of cardiac failure: the cardiac failure clinic

Daniel LOISANCE

Journal Article

Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in

Journal Article

Association of cardiac disease with the risk of post-lung transplantation mortality in Chinese recipients

Journal Article

Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock

Muhammad Furqan,Yamei Chen,Akintunde Akinleye,Judy Sarungbam,Alan Gass,Karen Seiter,Delong Liu

Journal Article

Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Journal Article

Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis

Wei Gong,Mengwen Yan,Junxiong Chen,Sandip Chaugai,Chen Chen,Daowen Wang

Journal Article

Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling

Samuel Chege Gitau,Xuelian Li,Dandan Zhao,Zhenfeng Guo,Haihai Liang,Ming Qian,Lifang Lv,Tianshi Li,Bozhi Xu,Zhiguo Wang,Yong Zhang,Chaoqian Xu,Yanjie Lu,Zhiming Du,Hongli Shan,Baofeng Yang

Journal Article

PAK1 is a novel cardiac protective signaling molecule

Yunbo Ke,Xin Wang,Xu Yu Jin,R. John Solaro,Ming Lei

Journal Article

Progressive failure analysis of notched composite plate by utilizing macro mechanics approach

Journal Article

Bending failure performance of a shield tunnel segment based on full-scale test and numerical analysis

Journal Article

Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Journal Article

Surficial stability analysis of soil slope under seepage based on a novel failure mode

Journal Article

LSSVM-based approach for refining soil failure criteria and calculating safety factor of slopes

Shiguo XIAO; Shaohong LI

Journal Article

Study of high-strength CFRP bolted joints with failure- monitoring cone washers

Tsukasa KATSUMATA, Yoshihiro MIZUTANI, Akira TODOROKI, Ryosuke MATSUZAKI

Journal Article

Analysis of stress and failure in rock specimens with closed and open flaws on the surface

Journal Article